Vulvar lichen sclerosus in women of reproductive age

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Vulvar Lichen Sclerosus et Atrophicus

Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatosis characterized by ivory-white plaques or patches with glistening surface commonly affecting the vulva and anus. Common symptoms are irritation, soreness, dyspareunia, dysuria, and urinary or fecal incontinence. Anogenital lichen sclerosus (LS) is characterized by porcelain-white atrophic plaques, which may become confluent extend...

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Vulvar lichen sclerosus: 11 women treated with tacrolimus 0.1% ointment.

Lichen sclerosus is a chronic relapsing disease, usually treated with ultra-potent corticosteroids. As immunological alterations are considered important aetiopathogenetic factors in lichen sclerosus, the new immunomodulating topical agents, such as tacrolimus and pimecrolimus, have been employed sporadically as alternative therapies. The aim of this study was to evaluate the therapeutic effect...

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Dermasilk briefs in vulvar lichen sclerosus: an adjuvant tool.

OBJECTIVE : The purpose of our study was to evaluate whether briefs made of Dermasilk fabric could be an adjuvant tool in the management of vulvar lichen sclerosus (LS). MATERIALS AND METHODS : A controlled, randomized, double-blind study versus placebo was conducted, comparing Dermasilk versus standard cotton briefs in patients affected by LS during treatment with clobetasol propionate 0.05%...

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Successful treatment of vulvar lichen sclerosus with topical tacrolimus.

A 19-year-old woman was admitted to our department with a history of itching and pain of the vulvar region. During a period of 6 months, her clinical symptoms had significantly deteriorated resulting in painful urination and defecation in addition to dyspareunia. Clinical examination showed well-demarcated, smooth, whitish shiny plaques that affected the labia minora, introitus vaginae, and the...

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Genital Vulvar Lichen Sclerosus in Monozygotic Twin Women: A Case Report and Review of the Literature

Lichen sclerosus et atrophicus is a skin disease of multifactorial etiology which appears in patients with genetic or hormonal predisposition and autoimmune disease. Genetic predisposition is suggested by familial reports of the disease which involve twins, siblings, and mother-daughter/son series. This is a report of the occurrence of lichen sclerosus et atrophicus in monozygotic twin women, s...

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ژورنال

عنوان ژورنال: Baylor University Medical Center Proceedings

سال: 2021

ISSN: 0899-8280,1525-3252

DOI: 10.1080/08998280.2021.1885093